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Join us in the Fight Against Niemann-Pick Type C Disease |
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ResearchCurrently Funded Grants as of 7/01/10 |
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Ara Parseghian Medical Research FoundationCurrently Funded Grants as of 10/01/2011Jian Cao, Ph.D. – Post Doctoral Research Associate, Stanford University School of Medicine – TITLE: “Genetic Approaches to NPC Disease” - $60,000
John M. Dietschy, M.D., Professor of Internal Medicine, UT Southwestern Medical Center – TITLE: “Request for Funding of Apparatus Required for Direct Administration of Biologically Active Compounds into the Brain of Mice with the NPC1 Mutation“ - $14,000 – funds provided by the BReaK Thru Fund
Guosheng Liang, Ph.D. – Assistant Professor, Molecular Genetics, UT Southwestern Medical Center at Dallas – TITLE: “NPC1 and NPC2-Mediated Cholesterol Binding and Transfer in the Pathogenesis of NPC Disease” - $70,000.
Benny Liu, M.D. ,John M. Dietschy, M.D.,– Professor of Internal Medicine, UT Southwestern Medical Center – TITLE: “Effects of Cyclodextrin Delivery via Intracerebral Ventricular Injections into NP-C Mice- $70,000
Frederick Maxfield, Ph.D. – Professor and Chairman, Biochemistry, Weill Medical College of Cornell University – TITLE: “Use of Histone Deacetylase Inhibitors (HDACi) in Clinical Trials” - $90,000.
Leslie McCauliff, Pre Doctoral Fellow /Judith Storch, Ph.D. –Professor of Nutritional Sciences, Rutgers University – TITLE: “Cholesterol Transport by NPC2 and Cyclodextrins”. - $130,929
Daniel S. Ory, M.D. – Professor of Medicine, Cell Biology and Physiology, Internal Medicine, Washington University – TITLE: “Oxysterols and Early Detection of NPC1 Disease for Newborn Screening” - $90,000.
Suzanne Pfeffer, Ph.D. – Professor, Biochemistry, Stanford University School of Medicine – TITLE: “Roles of NPC1 and NPC2 Proteins in Cholesterol Homeostasis” - $90,000.
Joyce Repa, Ph.D. – Assistant Professor, Physiology, UT Southwestern Medical Center at Dallas – TITLE: “Identifying the Molecular Mechanisms of Therapies for NPC Disease” - $90,000.
Kanagaraj Subramanian, Ph.D. – Research Associate, The Scripps Research Institute – TITLE: “Impact of Proteostasis Regulators on Correction of NPC1 Mutants triggering NPC disease” - $60,000 Paul Helquist, Ph.D. – University of Notre Dame, Department of Chemistry & Biochemistry. Research Team: Pauline Bourbon; Katherine Byrd; Aaron Byrd; Aaron Forbes; Tobias Ankner; Jonatan Kleimark; – TITLE: "Chemistry Core for NPC Research - Design and Synthesis of Therapeutic Agents and Molecular Probes"- Notre Dame sponsored research
David H. Thompson Ph.D. – Purdue University, - TITLE: “Development of Multivalent β-Cyclodextrin Polymer Contructs as Potential Delivery Vehicles for Niemann-Pick Type C Therapy” - $45,000 - funds provided by the BReaK Thru Fund
Deng Wei, Ph.D. – Purdue University, - TITLE: “Development of Multivalent β-Cyclodextrin Delivery Vehicles as Potential for Niemann-Pick Type C Therapeutics” - $25,000 - funds provided by the BReaK Thru Fund |
