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1. Philip Beachy, Ph.D. - Associate Professor, Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine - $220,000 award (2-year grant from 1/98 - 12/99)
   TITLE: "Cholesterol homeostasis and NP-C: A role in cell signaling?"



2. Krishna Bhat, Ph.D. - Emory University School of Medicine - $208,647 award (2-year grant from 7/01-6/03)
   TITLE: "NPC disease in Drosophila mutant for the tumor suppressor Patched")



3. Kendal Broadie, Ph.D. - Assistant Professor, Department of Biology, University of Utah - $250,000 award (2-year grant from 1/00 - 12/01)
   TITLE: "Neurological functions of NPC1 in Drosophila"



4. Maja Bucan, Ph.D. - Assistant Professor, College of Medicine, University of Pennsylvania - $250,000 award (2-year grant from 7/95 - 6/97)
   TITLE: "Genetic Mapping and Isolation of the mouse NP-C Disease Gene"



5. Robert Burgess, Ph.D. and Kevin Seburn, Ph.D. - The Jackson Laboratory -$5,000 award (1 year grant from 4/06-3/07)
   TITLE: "Characterization and development of a new mouse model of NP-C disease"



6. Eugene Carstea, Ph.D. - Senior Staff Fellowship Scientist, Developmental and Metabolic Neurology Branch, Neurology Institute, NIH - $250,000 award (2-year grant from 7/95 - 6/97)
   TITLE: "Integrative Efforts to Identify Gene for Niemann-Pick disease Type C"



7. Geoffrey Chang, Ph.D. - Associate Professor, The Scripps Research Institute - $96,000 award (1.5- year grant from 07/05-12/06)
   TITLE: "X-ray Structure of Niemann-Pick C1"



8. T.Y. Chang, Ph.D. - Professor of Biochemistry, Dartmouth Medical School - $151,844 award (2-year grant from 1/00 - 12/01)
   TITLE: "Role of NPC1 in Intracellular Cholesterol Trafficking"



9. Kumlesh Dev, Ph.D - Laboratory Head of Molecular and Cellular Neuroscience, Novartis Pharma A.G., Switzerland - $164,000 award (2-year grant from 10/04-09/06)
   TITLE: "Identification of Molecular Targets Linking Alzheimer's and Niemann-Pick Type C disease"



10. Robert Erickson, M.D. - Professor of Human Genetics and Inherited Diseases, University of Arizona College of Medicine - $141,666 award (2.5-year grant from 7/97 - 12/99)
    TITLE: "Cloning the Mouse Homolog of the Niemann-Pick C Gene"



11. William Garver, Ph.D. - Research Assistant Professor, Department of Pediatrics, University of Arizona – $285,009 award (5.5-year grant from 1/01 – 6/06)
    TITLE: "Research Projects for the Investigation of Niemann-Pick Type C disease”



12. Robert Gillies, Ph.D. - Professor, Biochemistry, University of Arizona College of Medicine - $157,465 award (2-year grant from 1/99 - 12/00)
    TITLE: Non-invasive Monitoring of NP-C Progression and Therapy with MRS/MRI"



13. Wenda Greer, Ph.D. - Associate Professor, Pathology Department, Dalhousie University, Halifax, Nova Scotia - $75,000 award (1-year grant from 8/96 - 7/97)
    TITLE: "Localizing the Niemann-Pick D Gene (Nova Scotia Variant of Type C)"



14. Richard Hawkes, Ph.D. - Professor, Department of Cell Biology & Anatomy, University of Calgary - $152,760 award (2-year grant from 1/00 - 12/01)
    TITLE: "Patterned Purkinje Cell Loss in the Cerebellum of a Murine Model of NPC: A Possible Neuroprotective Role for the Small Heat Shock Protein HSP25"



15. Elina Ikonen, M.D., Ph.D. - Senior Scientist of the Academy of Finland, National Public Health Institute, Helsinki, Finland - $347,500 award (2-year grant from 1/99 – 12/00) (1.5-year grant from 7/02 –12/03) (additional grant from 1/00 – 12/01)
    TITLE: "NPC Lesion at the Crossing of Cellular Cholesterol Trafficking Circuits"



16. Yiannis Ioannou, Ph.D. - Mt. Sinai School of Medicine - $250,000 award (2-year grant from 7/02 – 6/04) (Additional 6 years of awards totaling $719,902 from 3/96 – 6/02)
    TITLE: “Cellular and Molecular Studies of Niemann-Pick C Disease”



17. Toshihide Kobayashi, Ph.D. - Group Leader, Sphingolipid Functions Laboratory, RIKEN Frontier Research System, Japan - $125,000 award (1-year grant from 1/01 - 12/01)
    TITLE: "Effects of Cholesterol on Endocytic Pathway in NPC Cells"



18. Jeffrey Krise, Ph.D. - Assistant Professor, The University of Kansas - $125,000 award (1-year grant from 7/06 - 6/07)
    TITLE: "The Role of NPC1 in the intracellular trafficking of endogenous amines"



19. Yvonne Lange, Ph.D. - Professor, Department of Pathology, Rush Presbyterian - St. Lukes Medical Center - $103,796 award (1-year grant from 1/98 - 12/98)
    TITLE: "A Novel Treatment of Niemann-Pick Type C disease"



20. Laura Liscum, Ph.D. - Professor, Physiology, Tufts University School of Medicine - $295,690 award (3.5 year grant from 8/97 - 12/00)
    TITLE: "Analysis of Pharmaceutical Compounds that Correct the NPC Phenotype in Cultured Cells"



21. Emyr Lloyd-Evans, Ph.D. - Department of Biology, Oxford University – $46,000 award (6-month award during Fall 2005)
    TITLE: “Lysosomal Calcium Homeostasis Defect in NPC1 Cells that contribute to Endocytic Defects in NPC1”



22. Robert Maue, Ph.D. - Associate Professor, Departments of Physiology and Biochemistry, Dartmouth Medical School - $279,950 award (2.5-year grant from 7/97 - 12/99)
    TITLE: "Striatal and Hypothalamic Neuron Function in NP-C Mice"



23. Synthia Mellon, M.D. - Professor, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco - $537,500 award (4.5-year grant from 1/01 - 6/05)
    TITLE: "Therapeutic Strategies for Treatment of NP-C"



24. James Metherall, Ph.D. - Assistant Professor, Department of Human Genetics, University of Utah - $275,894 award (3-year grant from 8/95 - 7/98)
    TITLE: "Genetic Defects in Proteins Required for Intracellular Cholesterol Transport Cause NP-C"



25. Gilles Millat, Ph.D. - Assistant Professor, INSERM and Lyon University, France - $112,200 award (2-year grant from 1/03 - 12/04)
    TITLE: "Generation of Mice With Specific Mutations Affecting the Cysteine-rich Luminal Loop of the NPC1"
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27. Axel Nohturfft, Ph.D. - Assistant Professor, Department of Molecular and Cellular Biology, Harvard University - $394,463 award (4.5-year grant from 1/01 - 6/05)
    TITLE: "Role of Apolipoprotein E in Niemann-Pick disease Type C"



28. Richard Pagano, Ph.D. and David Marks, Ph.D. - Professors Department of Biochemistry & Molecular Biology, Mayo Clinic Rochester, MN -- $708,349 awarded (7-year grant period from 1/98 - 6/04)
    TITLE:" Correction of NP-C Phenotype by Rab Overexpression"



29. Leo Pallanck, Ph.D. - Assistant Professor, Genome Sciences, University of Washington – $306,866 award (4-year grant period from 7/02 – 6/06)
    TITLE: “Development of a Drosophila Model of Niemann-Pick Type C Disease”



30. William Pavan, Ph.D. - Section Chief, Laboratory of Genetic Disease Research, NIH - $246,060 award (3-year grant from 7/95 - 6/98)
    TITLE: "Exploiting Mouse Models to Identify the Gene for NP-C"



31. David Pearce, Ph.D. - Assistant Professor, Biochemistry and Biophysics, University of Rochester School of Medicine & Dentistry - $83,187 award - (1-year grant from 1/00 - 12/00)
    TITLE: "A Yeast Model for Studying Niemann-Pick Type C"



32. Frank Pfrieger, Ph.D. -- Assistant Professor, Centre de Neurochimie, Stasbourg, France - $200,00 award (2-year grant from 7/02-6/04)
    TITLE:" Role of NPC1 in Cholesterol Shuttle from Glia to Neurons"



33. Frances Platt, Ph.D. – Reader of Glycobiology, University of Oxford - $499,052 award (4-year award from 7/02 – 6/06)
    TITLE: "Cell Biology of Niemann-Pick C disease: Role of glycosphingolipids in Pathology"

34. James Shayman, M.D. - Professor of Internal Medicine, University of Michigan $102,947 award - (1-year grant from 3/00 - 2/01)
    TITLE: "Treatment of NPC-1 with Glucosylceramide Synthase Inhibitors"



35. Kyra L. Somers, D.V.M., Ph.D. - Assistant Professor, Microbiology, Immunology and Pathology, Colorado State University - $52,581 award (1-year award from 7/04-2/05)
    TITLE: "Feline Niemann-Pick C1 Disease"



36. Ann Stock, Ph.D. - Professor, UMDNJ - Robert Wood Johnson Medical School Center for Advanced Biotechnology & Medicine & Associate Investigator, HHMI - $530,556 award (4.5-year award from 1/03-6/07)
    TITLE: "Structural Analysis of NPC2"



37. Jerome Strauss III, Ph.D. - Professor, Obstetrics and Gynecology, University of Pennsylvania $313,654 award - (6-year award from 1/98 - 12/03)
    TITLE: "Function of MLN"



38. Stephen Sturley, Ph.D.- Assistant Professor, Institute of Human Nutrition, Columbia University - $1,320,000 award (10-year grant from 8/97-6/07)
    TITLE: "A genetic model of Niemann-Pick Type C disease"



39. Kinuko Suzuki, M.D. - Professor of Pathology and Laboratory Medicine, University of North Carolina - $203,247 award (2-year grant from 1/00 - 12/01)
    TITLE: "Neuronal Death and Glial Cell Reactions in NP-C Mouse"



40. Derek Symula, Ph.D. - Research Scientist IV, Genomics Institute Wadsworth Center - $90,000 award (1-year grant from 01/06-12/06)
    TITLE: "Genetic Modifiers of NPC2 Deficiency in Mice"



41. Danilo Tagle, Ph.D. - Head - Molecular Neurogenetics Section, NIH - $83,000 award (1-year grant from 8/97 - 7/98)
    TITLE: "Characterization of the Niemann-Pick Type C Gene Product (NPC1)"



42. Alan Tall, M.D. - Professor in Medicine, Columbia University - $200,200 award (2-year grant from 1/98 - 12/99)
    TITLE: "Atherosclerosis and Reverse Lipid Transport in NPC"



43. James Thomas, Ph.D. - Professor, Department of Genetics, University of Washington - $120,000 award (2-year grant from 7/1/00 - 6/30/02)
    TITLE: “Genetic and Cellular Analysis of a C.elegans Model for Niemann-Pick Type C disease.”



44. Ted Trouard, Ph.D. - Associate Professor, Biomedical Engineering and Radiology, University of Arizona, - $17,000 award (Spring 2006)
    TITLE: “Non-invasive Imaging to Detect and Monitor the Progression of NPC Disease and its Response to Therapy”



45. Jean Eaton Vance, Ph.D. - Professor, Heritage Medical Research Center, University of Alberta, Canada - $782,936 award (5.5 year grant from 1/00 – 6/06)
    TITLE: “Role of NPC1 in Primary Cultures of Murine Neurons”



46. Inez Vincent, Ph.D.-Research Associate Professor, Department of Pathology, University of Washington-$45,000 award (1-year grant from 1/1/03-12/31/03)
    TITLE: "Cdk Inhibitors for Treating NPC"



47. NP-C Genetic Counseling and Carrier Testing Center - Mayo Clinic, Rochester, MN - genetic counselor, Cate Walsh-Vockley

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